Cargando…

Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats

Urolithiasis was induced using ethylene glycol in wistar albino rats, the formation of calcium stones in the kidney results with the damage of antioxidant system. Ethanolic extract of Cucumis trigonus Roxb fruit of family Curcurbitaceae was used to treat urolithiasis. On this course, the extract als...

Descripción completa

Detalles Bibliográficos
Autores principales: Balakrishnan, A., Kokilavani, R, Gurusamy, K., Teepa, K. S. Ananta, Sathya, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377036/
https://www.ncbi.nlm.nih.gov/pubmed/22736884
_version_ 1782235907204579328
author Balakrishnan, A.
Kokilavani, R
Gurusamy, K.
Teepa, K. S. Ananta
Sathya, M.
author_facet Balakrishnan, A.
Kokilavani, R
Gurusamy, K.
Teepa, K. S. Ananta
Sathya, M.
author_sort Balakrishnan, A.
collection PubMed
description Urolithiasis was induced using ethylene glycol in wistar albino rats, the formation of calcium stones in the kidney results with the damage of antioxidant system. Ethanolic extract of Cucumis trigonus Roxb fruit of family Curcurbitaceae was used to treat urolithiasis. On this course, the extract also repairs the changes that happened in the enzymatic, non enzymatic antioxidants and lipid peroxidation in liver and kidney of urolithiasis induced rats. The results obtained from the analysis were compared at 5% level of significance using one way ANOVA. The results show that the ethanolic fruit extract has repaired the levels of antioxidants and malondialdehyde to their normal levels.
format Online
Article
Text
id pubmed-3377036
institution National Center for Biotechnology Information
language English
publishDate 2011
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-33770362012-06-25 Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats Balakrishnan, A. Kokilavani, R Gurusamy, K. Teepa, K. S. Ananta Sathya, M. Anc Sci Life Original Article Urolithiasis was induced using ethylene glycol in wistar albino rats, the formation of calcium stones in the kidney results with the damage of antioxidant system. Ethanolic extract of Cucumis trigonus Roxb fruit of family Curcurbitaceae was used to treat urolithiasis. On this course, the extract also repairs the changes that happened in the enzymatic, non enzymatic antioxidants and lipid peroxidation in liver and kidney of urolithiasis induced rats. The results obtained from the analysis were compared at 5% level of significance using one way ANOVA. The results show that the ethanolic fruit extract has repaired the levels of antioxidants and malondialdehyde to their normal levels. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3377036/ /pubmed/22736884 Text en Copyright: © Ancient Science of Life http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Balakrishnan, A.
Kokilavani, R
Gurusamy, K.
Teepa, K. S. Ananta
Sathya, M.
Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
title Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
title_full Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
title_fullStr Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
title_full_unstemmed Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
title_short Effect of ethanolic fruit extract of Cucumis trigonus Roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
title_sort effect of ethanolic fruit extract of cucumis trigonus roxb. on antioxidants and lipid peroxidation in urolithiasis induced wistar albino rats
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377036/
https://www.ncbi.nlm.nih.gov/pubmed/22736884
work_keys_str_mv AT balakrishnana effectofethanolicfruitextractofcucumistrigonusroxbonantioxidantsandlipidperoxidationinurolithiasisinducedwistaralbinorats
AT kokilavanir effectofethanolicfruitextractofcucumistrigonusroxbonantioxidantsandlipidperoxidationinurolithiasisinducedwistaralbinorats
AT gurusamyk effectofethanolicfruitextractofcucumistrigonusroxbonantioxidantsandlipidperoxidationinurolithiasisinducedwistaralbinorats
AT teepaksananta effectofethanolicfruitextractofcucumistrigonusroxbonantioxidantsandlipidperoxidationinurolithiasisinducedwistaralbinorats
AT sathyam effectofethanolicfruitextractofcucumistrigonusroxbonantioxidantsandlipidperoxidationinurolithiasisinducedwistaralbinorats