Cargando…
To live or to die: a matter of processing damaged DNA termini in neurons
Defects in the repair of deoxyribonucleic acid (DNA) damage underpin several hereditary neurological diseases in humans. Of the different activities that repair chromosomal DNA breaks, defects in resolving damaged DNA termini are among the most common causes of neuronal cell death. Here, the molecul...
Autor principal: | El-Khamisy, Sherif F |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
WILEY-VCH Verlag
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377058/ https://www.ncbi.nlm.nih.gov/pubmed/21246735 http://dx.doi.org/10.1002/emmm.201000114 |
Ejemplares similares
-
DNA damage as a mechanism of neurodegeneration in ALS and a contributor to astrocyte toxicity
por: Kok, Jannigje Rachel, et al.
Publicado: (2021) -
Perturbed autophagy and DNA repair converge to promote neurodegeneration in amyotrophic lateral sclerosis and dementia
por: Walker, Callum, et al.
Publicado: (2018) -
DNA Homeostasis and Senescence: Lessons from the Naked Mole Rat
por: Boughey, Harvey, et al.
Publicado: (2021) -
The Complex Mechanisms by Which Neurons Die Following DNA Damage in Neurodegenerative Diseases
por: Shadfar, Sina, et al.
Publicado: (2022) -
TDP2/TTRAP Is the Major 5′-Tyrosyl DNA Phosphodiesterase Activity in Vertebrate Cells and Is Critical for Cellular Resistance to Topoisomerase II-induced DNA Damage
por: Zeng, Zhihong, et al.
Publicado: (2011)