SASPase regulates stratum corneum hydration through profilaggrin-to-filaggrin processing

The stratum corneum (SC), the outermost layer of the epidermis, acts as a barrier against the external environment. It is hydrated by endogenous humectants to avoid desiccation. However, the molecular mechanisms of SC hydration remain unclear. We report that skin-specific retroviral-like aspartic pr...

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Detalles Bibliográficos
Autores principales: Matsui, Takeshi, Miyamoto, Kenichi, Kubo, Akiharu, Kawasaki, Hiroshi, Ebihara, Tamotsu, Hata, Kazuya, Tanahashi, Shinya, Ichinose, Shizuko, Imoto, Issei, Inazawa, Johji, Kudoh, Jun, Amagai, Masayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377080/
https://www.ncbi.nlm.nih.gov/pubmed/21542132
http://dx.doi.org/10.1002/emmm.201100140

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