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Demyelination and axonal preservation in a transgenic mouse model of Pelizaeus-Merzbacher disease

It is widely thought that demyelination contributes to the degeneration of axons and, in combination with acute inflammatory injury, is responsible for progressive axonal loss and persistent clinical disability in inflammatory demyelinating disease. In this study we sought to characterize the relati...

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Detalles Bibliográficos
Autores principales: Edgar, Julia M, McCulloch, Mailis C, Montague, Paul, Brown, Angus M, Thilemann, Sebastian, Pratola, Laura, Gruenenfelder, Fredrik I, Griffiths, Ian R, Nave, Klaus-Armin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377270/
https://www.ncbi.nlm.nih.gov/pubmed/20091761
http://dx.doi.org/10.1002/emmm.200900057