1q12 chromosome translocations form aberrant heterochromatic foci associated with changes in nuclear architecture and gene expression in B cell lymphoma

Epigenetic perturbations are increasingly described in cancer cells where they are thought to contribute to deregulated gene expression and genome instability. Here, we report the first evidence that a distinct category of chromosomal translocations observed in human tumours—those targeting 1q12 sat...

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Detalles Bibliográficos
Autores principales: Fournier, Alexandra, McLeer-Florin, Anne, Lefebvre, Christine, Duley, Samuel, Barki, Leila, Ribeyron, Juliana, Kassambara, Alboukadel, Hamaidia, Sieme, Granjon, Aurélie, Gressin, Rémy, Lajmanovich, Alicia, Bonnefoix, Thierry, Chauvelier, Stéphanie, Debernardi, Alexandra, Rousseaux, Sophie, de Fraipont, Florence, Figeac, Martin, Kerckaert, Jean-Pierre, De Vos, John, Usson, Yves, Delaval, Katia, Grichine, Alexei, Vourc'h, Claire, Khochbin, Saadi, Feil, Robert, Leroux, Dominique, Callanan, Mary B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377314/
https://www.ncbi.nlm.nih.gov/pubmed/20432501
http://dx.doi.org/10.1002/emmm.201000067

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