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Mutations for the people

Similar cancer types may nevertheless differ widely in the genetic mutations they carry. In this Closeup, Kristensen and Borresen-Dale discuss how identifying these mutations can define which therapy is most likely to succeed in eliminating the cancerous cells and how the methodology developed by Di...

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Detalles Bibliográficos
Autores principales: Kristensen, Vessela, Borresen-Dale, Anne-Lise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377315/
https://www.ncbi.nlm.nih.gov/pubmed/20461736
http://dx.doi.org/10.1002/emmm.201000071
Descripción
Sumario:Similar cancer types may nevertheless differ widely in the genetic mutations they carry. In this Closeup, Kristensen and Borresen-Dale discuss how identifying these mutations can define which therapy is most likely to succeed in eliminating the cancerous cells and how the methodology developed by Dias-Santagata et al and described in this issue, is an important step in making mutation screening a reality in the clinical practice worldwide.