Oxidative stress promotes myofibroblast differentiation and tumour spreading

JunD regulates genes involved in antioxidant defence. We took advantage of the chronic oxidative stress resulting from junD deletion to examine the role of reactive oxygen species (ROS) in tumour development. In a model of mammary carcinogenesis, junD inactivation increased tumour incidence and reve...

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Detalles Bibliográficos
Autores principales: Toullec, Aurore, Gerald, Damien, Despouy, Gilles, Bourachot, Brigitte, Cardon, Melissa, Lefort, Sylvain, Richardson, Marion, Rigaill, Guillem, Parrini, Maria-Carla, Lucchesi, Carlo, Bellanger, Dorine, Stern, Marc-Henri, Dubois, Thierry, Sastre-Garau, Xavier, Delattre, Olivier, Vincent-Salomon, Anne, Mechta-Grigoriou, Fatima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377319/
https://www.ncbi.nlm.nih.gov/pubmed/20535745
http://dx.doi.org/10.1002/emmm.201000073

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