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Prion protein in Alzheimer's pathogenesis: a hot and controversial issue

The role for cellular prion protein PrP(c) in β-amyloid (Aβ) oligomer-induced synaptic impairment is a topic of great interest and some controversy. In this issue of EMBO Molecular Medicine Aguzzi and co-workers explore the contribution of PrP(c) to deficient long term potentiation (LTP) and soluble...

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Detalles Bibliográficos
Autores principales: Benilova, Iryna, De Strooper, Bart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377329/
https://www.ncbi.nlm.nih.gov/pubmed/20698011
http://dx.doi.org/10.1002/emmm.201000088