Selective targeting of neuroblastoma tumour-initiating cells by compounds identified in stem cell-based small molecule screens

Neuroblastoma (NB) is the most deadly extra-cranial solid tumour in children necessitating an urgent need for effective and less toxic treatments. One reason for the lack of efficacious treatments may be the inability of existing drugs to target the tumour-initiating or cancer stem cell population r...

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Detalles Bibliográficos
Autores principales: Smith, Kristen M, Datti, Alessandro, Fujitani, Mayumi, Grinshtein, Natalie, Zhang, Libo, Morozova, Olena, Blakely, Kim M, Rotenberg, Susan A, Hansford, Loen M, Miller, Freda D, Yeger, Herman, Irwin, Meredith S, Moffat, Jason, Marra, Marco A, Baruchel, Sylvain, Wrana, Jeffrey L, Kaplan, David R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377336/
https://www.ncbi.nlm.nih.gov/pubmed/20721990
http://dx.doi.org/10.1002/emmm.201000093

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