Cargando…

Endothelial FAK is required for tumour angiogenesis

Mostrar otras versiones (1)

Focal adhesion kinase (FAK) is a cytoplasmic tyrosine kinase that plays a fundamental role in integrin and growth factor mediated signalling and is an important player in cell migration and proliferation, processes vital for angiogenesis. However, the role of FAK in adult pathological angiogenesis i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tavora, Bernardo, Batista, Silvia, Reynolds, Louise E, Jadeja, Shalini, Robinson, Stephen, Kostourou, Vassiliki, Hart, Ian, Fruttiger, Marcus, Parsons, Maddy, Hodivala-Dilke, Kairbaan M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	WILEY-VCH Verlag 2010
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377344/ https://www.ncbi.nlm.nih.gov/pubmed/21154724 http://dx.doi.org/10.1002/emmm.201000106

Ejemplares similares

Endothelial FAK is required for tumour angiogenesis
por: Tavora, Bernardo, et al.
Publicado: (2016)

FAK-heterozygous mice display enhanced tumour angiogenesis
por: Kostourou, Vassiliki, et al.
Publicado: (2013)

Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
por: Lechertier, Tanguy, et al.
Publicado: (2020)

Acute, but not constitutive, loss of endothelial β3-integrin inhibits tumour growth and angiogenesis
por: Steri, Veronica, et al.
Publicado: (2013)

Author Correction: Pericyte FAK negatively regulates Gas6/Axl signalling to suppress tumour angiogenesis and tumour growth
por: Lechertier, Tanguy, et al.
Publicado: (2023)

Phosphorylation of pericyte FAK-Y861 affects tumour cell apoptosis and tumour blood vessel regression
por: Lees, Delphine M., et al.
Publicado: (2021)

Stromal Claudin14-Heterozygosity, but Not Deletion, Increases Tumour Blood Leakage without Affecting Tumour Growth
por: Baker, Marianne, et al.
Publicado: (2013)

Correction to: Phosphorylation of pericyte FAK‑Y861 affects tumour cell apoptosis and tumour blood vessel regression
por: Lees, Delphine M., et al.
Publicado: (2021)

Tumour-associated endothelial-FAK correlated with molecular sub-type and prognostic factors in invasive breast cancer
por: Alexopoulou, Annika N, et al.
Publicado: (2014)

Focal Adhesion Kinase (FAK) tyrosine 397E mutation restores the vascular leakage defect in endothelium‐specific FAK‐kinase dead mice
por: Alexopoulou, Annika N, et al.
Publicado: (2017)

Endothelial-Rac1 Is Not Required for Tumor Angiogenesis unless αvβ3-Integrin Is Absent
por: D'Amico, Gabriela, et al.
Publicado: (2010)

Fascin 1 is dispensable for developmental and tumour angiogenesis
por: Ma, Yafeng, et al.
Publicado: (2013)

Novel roles for integrins in tumour angiogenesis
por: Germain, M, et al.
Publicado: (2006)

ERG activity is regulated by endothelial FAK coupling with TRIM25/USP9x in vascular patterning
por: D'Amico, Gabriela, et al.
Publicado: (2022)

Endogenous ribosomal protein L29 (RPL29): a newly identified regulator of angiogenesis in mice
por: Jones, Dylan T., et al.
Publicado: (2013)

“Splitting the matrix”: intussusceptive angiogenesis meets MT1‐MMP
por: D'Amico, Gabriela, et al.
Publicado: (2019)

αvβ3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration
por: Worth, Daniel C., et al.
Publicado: (2010)

Suppression of Endothelial Cell FAK Expression Reduces Pancreatic Ductal Adenocarcinoma Metastasis after Gemcitabine Treatment
por: Roy-Luzarraga, Marina, et al.
Publicado: (2022)

Dual role of pericyte α6β1-integrin in tumour blood vessels
por: Reynolds, Louise E., et al.
Publicado: (2017)

Tumour angiogenesis is reduced in the Tc1 mouse model of Down Syndrome
por: Reynolds, Louise E., et al.
Publicado: (2010)

Dimethylarginine dimethylaminohydrolase I enhances tumour growth and angiogenesis
por: Kostourou, V, et al.
Publicado: (2002)

Association of Low Tumor Endothelial Cell pY397–Focal Adhesion Kinase Expression With Survival in Patients With Neoadjuvant-Treated Locally Advanced Breast Cancer
por: Roy-Luzarraga, Marina, et al.
Publicado: (2020)

Pancreatic stellate cells regulate blood vessel density in the stroma of pancreatic ductal adenocarcinoma
por: Di Maggio, Francesco, et al.
Publicado: (2016)

Novel Roles for α3β1 Integrin as a Regulator of Cytoskeletal Assembly and as a Trans-dominant Inhibitor of Integrin Receptor Function in Mouse Keratinocytes
por: Hodivala-Dilke, Kairbaan M., et al.
Publicado: (1998)

Endothelial cell talin1 is essential for embryonic angiogenesis
por: Monkley, Susan J., et al.
Publicado: (2011)

Cancer associated fibroblast FAK regulates malignant cell metabolism
por: Demircioglu, Fevzi, et al.
Publicado: (2020)

The role of tumour-derived iNOS in tumour progression and angiogenesis
por: Kostourou, V, et al.
Publicado: (2011)

α3β1 Integrin Is Required for Normal Development of the Epidermal Basement Membrane
por: DiPersio, C. Michael, et al.
Publicado: (1997)

Improved Immunotherapy Efficacy by Vascular Modulation
por: Newport, Emma L., et al.
Publicado: (2021)

Protrudin regulates FAK activation, endothelial cell migration and angiogenesis
por: Arora, Amita, et al.
Publicado: (2022)

The Adhesome Network: Key Components Shaping the Tumour Stroma
por: Nikolopoulou, Pinelopi A., et al.
Publicado: (2021)

The Endothelial Transcription Factor ERG Promotes Vascular Stability and Growth through Wnt/β-Catenin Signaling
por: Birdsey, Graeme M., et al.
Publicado: (2015)

Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK
por: Weis, Sara M., et al.
Publicado: (2008)

Redistribution of Adhesive Forces through Src/FAK Drives Contact Inhibition of Locomotion in Neural Crest
por: Roycroft, Alice, et al.
Publicado: (2018)

C-type natriuretic peptide co-ordinates cardiac structure and function
por: Moyes, Amie J, et al.
Publicado: (2020)

Repurposing an anti‐cancer agent for the treatment of hypertrophic heart disease
por: Dukinfield, Matthew, et al.
Publicado: (2019)

Gene Expression Analysis in Human Breast Cancer Associated Blood Vessels
por: Jones, Dylan T., et al.
Publicado: (2012)

Pancreatic Cancer Chemotherapy Is Potentiated by Induction of Tertiary Lymphoid Structures in Mice
por: Delvecchio, Francesca R., et al.
Publicado: (2021)

Editorial: Integrin adhesion receptors in health and disease
por: Kostourou, Vassiliki, et al.
Publicado: (2023)

Single-cell transcriptome analyses reveal novel targets modulating cardiac neovascularization by resident endothelial cells following myocardial infarction
por: Li, Ziwen, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_2st53aha6a8tdr4dj4f7nsovhj