Regulation of the severity of neuroinflammation and demyelination by TLR-ASK1-p38 pathway

Apoptosis signal-regulating kinase 1 (ASK1) is an evolutionarily conserved mitogen-activated protein kinase (MAPK) kinase kinase which plays important roles in stress and immune responses. Here, we show that ASK1 deficiency attenuates neuroinflammation in experimental autoimmune encephalomyelitis (E...

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Detalles Bibliográficos
Autores principales: Guo, Xiaoli, Harada, Chikako, Namekata, Kazuhiko, Matsuzawa, Atsushi, Camps, Monsterrat, Ji, Hong, Swinnen, Dominique, Jorand-Lebrun, Catherine, Muzerelle, Mathilde, Vitte, Pierre-Alain, Rückle, Thomas, Kimura, Atsuko, Kohyama, Kuniko, Matsumoto, Yoh, Ichijo, Hidenori, Harada, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2010
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377347/
https://www.ncbi.nlm.nih.gov/pubmed/21064192
http://dx.doi.org/10.1002/emmm.201000103

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