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Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010

To determine clinical characteristics of patients hospitalized in the United Kingdom with pandemic (H1N1) 2009, we studied 1,520 patients in 75 National Health Service hospitals. We characterized patients who acquired influenza nosocomially during the pandemic (H1N1) 2009 outbreak. Of 30 patients, 1...

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Autores principales: Enstone, Joanne E., Myles, Puja R., Openshaw, Peter J.M., Gadd, Elaine M., Lim, Wei Shen, Semple, Malcolm G., Read, Robert C., Taylor, Bruce L., McMenamin, James, Armstrong, Colin, Bannister, Barbara, Nicholson, Karl G., Nguyen-Van-Tam, Jonathan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Centers for Disease Control and Prevention 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377421/
https://www.ncbi.nlm.nih.gov/pubmed/21470446
http://dx.doi.org/10.3201/eid1704.101679
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author Enstone, Joanne E.
Myles, Puja R.
Openshaw, Peter J.M.
Gadd, Elaine M.
Lim, Wei Shen
Semple, Malcolm G.
Read, Robert C.
Taylor, Bruce L.
McMenamin, James
Armstrong, Colin
Bannister, Barbara
Nicholson, Karl G.
Nguyen-Van-Tam, Jonathan S.
author_facet Enstone, Joanne E.
Myles, Puja R.
Openshaw, Peter J.M.
Gadd, Elaine M.
Lim, Wei Shen
Semple, Malcolm G.
Read, Robert C.
Taylor, Bruce L.
McMenamin, James
Armstrong, Colin
Bannister, Barbara
Nicholson, Karl G.
Nguyen-Van-Tam, Jonathan S.
author_sort Enstone, Joanne E.
collection PubMed
description To determine clinical characteristics of patients hospitalized in the United Kingdom with pandemic (H1N1) 2009, we studied 1,520 patients in 75 National Health Service hospitals. We characterized patients who acquired influenza nosocomially during the pandemic (H1N1) 2009 outbreak. Of 30 patients, 12 (80%) of 15 adults and 14 (93%) of 15 children had serious underlying illnesses. Only 12 (57%) of 21 patients who received antiviral therapy did so within 48 hours after symptom onset, but 53% needed escalated care or mechanical ventilation; 8 (27%) of 30 died. Despite national guidelines and standardized infection control procedures, nosocomial transmission remains a problem when influenza is prevalent. Health care workers should be routinely offered influenza vaccine, and vaccination should be prioritized for all patients at high risk. Staff should remain alert to the possibility of influenza in patients with complex clinical problems and be ready to institute antiviral therapy while awaiting diagnosis during influenza outbreaks.
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spelling pubmed-33774212012-06-20 Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010 Enstone, Joanne E. Myles, Puja R. Openshaw, Peter J.M. Gadd, Elaine M. Lim, Wei Shen Semple, Malcolm G. Read, Robert C. Taylor, Bruce L. McMenamin, James Armstrong, Colin Bannister, Barbara Nicholson, Karl G. Nguyen-Van-Tam, Jonathan S. Emerg Infect Dis Research To determine clinical characteristics of patients hospitalized in the United Kingdom with pandemic (H1N1) 2009, we studied 1,520 patients in 75 National Health Service hospitals. We characterized patients who acquired influenza nosocomially during the pandemic (H1N1) 2009 outbreak. Of 30 patients, 12 (80%) of 15 adults and 14 (93%) of 15 children had serious underlying illnesses. Only 12 (57%) of 21 patients who received antiviral therapy did so within 48 hours after symptom onset, but 53% needed escalated care or mechanical ventilation; 8 (27%) of 30 died. Despite national guidelines and standardized infection control procedures, nosocomial transmission remains a problem when influenza is prevalent. Health care workers should be routinely offered influenza vaccine, and vaccination should be prioritized for all patients at high risk. Staff should remain alert to the possibility of influenza in patients with complex clinical problems and be ready to institute antiviral therapy while awaiting diagnosis during influenza outbreaks. Centers for Disease Control and Prevention 2011-04 /pmc/articles/PMC3377421/ /pubmed/21470446 http://dx.doi.org/10.3201/eid1704.101679 Text en https://creativecommons.org/licenses/by/4.0/This is a publication of the U.S. Government. This publication is in the public domain and is therefore without copyright. All text from this work may be reprinted freely. Use of these materials should be properly cited.
spellingShingle Research
Enstone, Joanne E.
Myles, Puja R.
Openshaw, Peter J.M.
Gadd, Elaine M.
Lim, Wei Shen
Semple, Malcolm G.
Read, Robert C.
Taylor, Bruce L.
McMenamin, James
Armstrong, Colin
Bannister, Barbara
Nicholson, Karl G.
Nguyen-Van-Tam, Jonathan S.
Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010
title Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010
title_full Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010
title_fullStr Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010
title_full_unstemmed Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010
title_short Nosocomial Pandemic (H1N1) 2009, United Kingdom, 2009–2010
title_sort nosocomial pandemic (h1n1) 2009, united kingdom, 2009–2010
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377421/
https://www.ncbi.nlm.nih.gov/pubmed/21470446
http://dx.doi.org/10.3201/eid1704.101679
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