Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells

BACKGROUND: The Runt-related transcription factor Runx2 is essential for bone development but is also implicated in progression of several cancers of breast, prostate and bone, where it activates cancer-related genes and promotes invasive properties. The transforming growth factor β (TGF-β) family m...

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Detalles Bibliográficos
Autores principales: Tandon, Manish, Gokul, Karthiga, Ali, Syed A, Chen, Zujian, Lian, Jane, Stein, Gary S, Pratap, Jitesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377538/
https://www.ncbi.nlm.nih.gov/pubmed/22537242
http://dx.doi.org/10.1186/1476-4598-11-27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377538/
https://www.ncbi.nlm.nih.gov/pubmed/22537242
http://dx.doi.org/10.1186/1476-4598-11-27

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