Cargando…

Runx2 mediates epigenetic silencing of the bone morphogenetic protein-3B (BMP-3B/GDF10) in lung cancer cells

BACKGROUND: The Runt-related transcription factor Runx2 is essential for bone development but is also implicated in progression of several cancers of breast, prostate and bone, where it activates cancer-related genes and promotes invasive properties. The transforming growth factor β (TGF-β) family m...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tandon, Manish, Gokul, Karthiga, Ali, Syed A, Chen, Zujian, Lian, Jane, Stein, Gary S, Pratap, Jitesh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377538/ https://www.ncbi.nlm.nih.gov/pubmed/22537242 http://dx.doi.org/10.1186/1476-4598-11-27

Ejemplares similares

Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells
por: Tandon, Manish, et al.
Publicado: (2014)

Formation and characterization of BMP2/GDF5 and BMP4/GDF5 heterodimers
por: Gipson, Gregory R., et al.
Publicado: (2023)

Bone morphogenetic protein-3b (BMP-3b) is expressed in adipocytes and inhibits adipogenesis as a unique complex
por: Hino, J, et al.
Publicado: (2012)

Runx3 regulates iron metabolism via modulation of BMP signalling
por: Kim, Hyun‐Yi, et al.
Publicado: (2021)

Epigenetic Regulation of RUNX3 in Thyroid Carcinoma
por: Joung, Kyong Hye, et al.
Publicado: (2012)

Epigenetic inactivation of RUNX3 in colorectal cancer
por: Shin, Eung Jin, et al.
Publicado: (2018)

Polymorphisms Analysis of BMP15, GDF9 and BMPR1B in Tibetan Cashmere Goat (Capra hircus)
por: Song, Tianzeng, et al.
Publicado: (2023)

Quantitative analysis of bone morphogenetic protein 15 (BMP15) and growth differentiation factor 9 (GDF9) gene expression in calf and adult bovine ovaries
por: Hosoe, Misa, et al.
Publicado: (2011)

Epigenetic Repression of RUNX2 and OSX Promoters Controls the Nonmineralized State of the Periodontal Ligament
por: Gopinathan, Gokul, et al.
Publicado: (2023)

An investigation of the effects of BMPR1B, BMP15, and GDF9 genes on litter size in Ramlıç and Dağlıç sheep
por: Çelikeloğlu, Koray, et al.
Publicado: (2021)

Bone Morphogenetic Protein (BMP)-3b Gene Depletion Causes High Mortality in a Mouse Model of Neonatal Hypoxic-Ischemic Encephalopathy
por: Ogawa, Yuko, et al.
Publicado: (2018)

BMP15 and GDF9 Gene Mutations in Premature Ovarian Failure
por: Kumar, Ravindra, et al.
Publicado: (2017)

Serum Concentrations of GDF9 and BMP15 Across the Menstrual Cycle
por: Riepsamen, Angelique Helena, et al.
Publicado: (2021)

RUNX1/ETO blocks selectin-mediated adhesion via epigenetic silencing of PSGL-1
por: Ponnusamy, K, et al.
Publicado: (2015)

In Vitro Release of Bioactive Bone Morphogenetic Proteins (GDF5, BB-1, and BMP-2) from a PLGA Fiber-Reinforced, Brushite-Forming Calcium Phosphate Cement
por: Gunnella, Francesca, et al.
Publicado: (2019)

The Role of Runx2 in Microtubule Acetylation in Bone Metastatic Breast Cancer Cells
por: Othman, Ahmad, et al.
Publicado: (2022)

Expression of genes for bone morphogenetic proteins BMP-2, BMP-4 and BMP-6 in various parts of the human skeleton
por: Kochanowska, Iwona, et al.
Publicado: (2007)

Hemojuvelin and bone morphogenetic protein (BMP) signaling in iron homeostasis
por: Core, Amanda B., et al.
Publicado: (2014)

Bone Morphogenetic Protein (BMP) signaling in development and human diseases
por: Wang, Richard N., et al.
Publicado: (2014)

Epigenetic Silencing of DKK3 in Medulloblastoma
por: Valdora, Francesca, et al.
Publicado: (2013)

GDF-5 can act as a context-dependent BMP-2 antagonist
por: Klammert, Uwe, et al.
Publicado: (2015)

Oocyte-Secreted Serum Biomarkers GDF9 and BMP15 in Women with Endometriosis
por: Shamsa, Aiat, et al.
Publicado: (2022)

BMPR-1B, BMP-15 and GDF-9 genes structure and their relationship with litter size in six sheep breeds reared in Egypt
por: Saleh, Ahmed. A., et al.
Publicado: (2020)

Effects of New Mutations in BMPRIB, GDF9, BMP15, LEPR, and B4GALNT2 Genes on Litter Size in Sheep
por: Ji, Xuewen, et al.
Publicado: (2023)

RUNX3, EGR1 and SOX9B Form a Regulatory Cascade Required to Modulate BMP-Signaling during Cranial Cartilage Development in Zebrafish
por: Dalcq, Julia, et al.
Publicado: (2012)

Sustained delivery of the bone morphogenetic proteins BMP-2 and BMP-7 for cartilage repair and regeneration in osteoarthritis
por: Whitty, Ciara, et al.
Publicado: (2022)

Schisandrin B regulates MC3T3-E1 subclone 14 cells proliferation and differentiation through BMP2-SMADs-RUNX2-SP7 signaling axis
por: Wang, Xueni, et al.
Publicado: (2020)

Methylated Bone Morphogenetic Protein 3 (BMP3) Gene: Evaluation of Tumor Suppressor Function and Biomarker Potential in Biliary Cancer
por: Kisiel, John B, et al.
Publicado: (2013)

TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer
por: Gui, Tao, et al.
Publicado: (2021)

SARS Coronavirus 3b Accessory Protein Modulates Transcriptional Activity of RUNX1b
por: Varshney, Bhavna, et al.
Publicado: (2012)

Mutations in GDF5 Reveal a Key Residue Mediating BMP Inhibition by NOGGIN
por: Seemann, Petra, et al.
Publicado: (2009)

Identification of mutations in BMP15 and GDF9 genes associated with prolificacy of Markhoz goats
por: Ghoreishi, Hourad, et al.
Publicado: (2019)

Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells
por: Haubold, Maike, et al.
Publicado: (2010)

The use of bone morphogenetic proteins (BMP) and pseudarthrosis, a literature review()
por: Oliveira, Oberdan Ribeiro Gonçalves de, et al.
Publicado: (2016)

Epigenetic silencing of miR-342-3p in B cell lymphoma and its impact on autophagy
por: Zhang, Min Yue, et al.
Publicado: (2020)

Expression Analysis of the Prolific Candidate Genes, BMPR1B, BMP15, and GDF9 in Small Tail Han Ewes with Three Fecundity (FecB Gene) Genotypes
por: Tang, Jishun, et al.
Publicado: (2018)

RUNX Proteins as Epigenetic Modulators in Cancer
por: Yi, Hongyang, et al.
Publicado: (2022)

Runx2 Association with Progression of Prostate Cancer in Patients: Mechanisms Mediating Bone Osteolysis and Osteoblastic Metastatic Lesions
por: Akech, Jacqueline, et al.
Publicado: (2009)

The role of EZH2 and DNA methylation in the silencing of the tumour suppressor RUNX3 in colorectal cancer
por: Kodach, Liudmila L., et al.
Publicado: (2010)

Phylogenetic evidence for independent origins of GDF1 and GDF3 genes in anurans and mammals
por: Opazo, Juan C., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rj6llsb2u48tpca9he1unotujp