Altered Cigarette Smoke-Induced Lung Inflammation Due to Ablation of Grx1

Glutaredoxins (Grx) are redox enzymes that remove glutathione bound to protein thiols, know as S-glutathionylation (PSSG). PSSG is a reservoir of GSH and can affect the function of proteins. It inhibits the NF-κB pathway and LPS aspiration in Grx1 KO mice with decreased inflammatory cytokine levels....

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Detalles Bibliográficos
Autores principales: Kuipers, Ine, Bracke, Ken R., Brusselle, Guy G., Aesif, Scott W., Krijgsman, Renske, Arts, Ilja C., Wouters, Emiel F. M., Reynaert, Niki L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377591/
https://www.ncbi.nlm.nih.gov/pubmed/22723915
http://dx.doi.org/10.1371/journal.pone.0038984

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377591/
https://www.ncbi.nlm.nih.gov/pubmed/22723915
http://dx.doi.org/10.1371/journal.pone.0038984

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