Cargando…
PET Imaging a MPTP-Induced Mouse Model of Parkinson’s Disease Using the Fluoropropyl-Dihydrotetrabenazine Analog [(18)F]-DTBZ (AV-133)
Parkinson’s disease (PD) is characterized by the loss of dopamine-producing neurons in the nigrostriatal system. Numerous researchers in the past have attempted to track the progression of dopaminergic depletion in PD. We applied a quantitative non-invasive PET imaging technique to follow this degen...
Autores principales: | Toomey, James S., Bhatia, Shilpa, Moon, La’Wanda T., Orchard, Elysse A., Tainter, Kerrie H., Lokitz, Stephen J., Terry, Tracee, Mathis, J. Michael, Penman, Andrew D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377623/ https://www.ncbi.nlm.nih.gov/pubmed/22723923 http://dx.doi.org/10.1371/journal.pone.0039041 |
Ejemplares similares
-
Quantitative analysis of the therapeutic effect of magnolol on MPTP-induced mouse model of Parkinson’s disease using in vivo (18)F-9-fluoropropyl-(+)-dihydrotetrabenazine PET imaging
por: Weng, Chi-Chang, et al.
Publicado: (2017) -
A Multi-Atlas-Based [18F]9-Fluoropropyl-(+)-Dihydrotetrabenazine Positron Emission Tomography Image Segmentation Method for Parkinson’s Disease Quantification
por: Pan, Yiwei, et al.
Publicado: (2022) -
PET Imaging of VMAT2 with the Novel Radioligand [(18)F]FE-DTBZ-d4 in Nonhuman Primates: Comparison with [(11)C]DTBZ and [(18)F]FE-DTBZ
por: Nag, Sangram, et al.
Publicado: (2021) -
Differences in Dihydrotetrabenazine Isomer Concentrations Following Administration of Tetrabenazine and Valbenazine
por: Skor, Heather, et al.
Publicado: (2017) -
Genetic Incorporation of Human Metallothionein into the Adenovirus Protein IX for Non-Invasive SPECT Imaging
por: Mathis, J. Michael, et al.
Publicado: (2011)