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Murine but Not Human Basophil Undergoes Cell-Specific Proteolysis of a Major Endoplasmic Reticulum Chaperone

INTRODUCTION: Basophil has been implicated in anti-parasite defense, allergy and in polarizing T(H)2 response. Mouse model has been commonly used to study basophil function although the difference between human and mouse basophils is underappreciated. As an essential chaperone for multiple Toll-like...

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Detalles Bibliográficos
Autores principales: Liu, Bei, Staron, Matthew, Li, Zihai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377640/
https://www.ncbi.nlm.nih.gov/pubmed/22724016
http://dx.doi.org/10.1371/journal.pone.0039442