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Up-Regulation of Annexin-A1 and Lipoxin A(4) in Individuals with Ulcerative Colitis May Promote Mucosal Homeostasis

BACKGROUND: One of the characteristics of an active episode of ulcerative colitis (UC) is the intense mucosal infiltration of leukocytes. The pro-resolution mediators Annexin-A1 (AnxA1) and lipoxin A(4) (LXA(4)) exert counter-regulatory effects on leukocyte recruitment, however to date, the dual/cum...

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Detalles Bibliográficos
Autores principales: Vong, Linda, Ferraz, Jose G. P., Dufton, Neil, Panaccione, Remo, Beck, Paul L., Sherman, Philip M., Perretti, Mauro, Wallace, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377644/
https://www.ncbi.nlm.nih.gov/pubmed/22723974
http://dx.doi.org/10.1371/journal.pone.0039244