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Mouse Dendritic Cells Pulsed with Capsular Polysaccharide Induce Resistance to Lethal Pneumococcal Challenge: Roles of T Cells and B Cells

Mice are exceedingly sensitive to intra-peritoneal (IP) challenge with some virulent pneumococci (LD50 = 1 bacterium). To investigate how peripheral contact with bacterial capsular polysaccharide (PS) antigen can induce resistance, we pulsed bone marrow dendritic cells (BMDC) of C57BL/6 mice with ty...

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Detalles Bibliográficos
Autores principales:	Cohen, Noam, Margalit, Raanan, Pevsner-Fischer, Meirav, Yona, Simon, Jung, Steffen, Eisenbach, Lea, Cohen, Irun R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377650/ https://www.ncbi.nlm.nih.gov/pubmed/22723962 http://dx.doi.org/10.1371/journal.pone.0039193

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