Human SOD2 Modification by Dopamine Quinones Affects Enzymatic Activity by Promoting Its Aggregation: Possible Implications for Parkinson’s Disease

Mitochondrial dysfunction and oxidative stress are considered central in dopaminergic neurodegeneration in Parkinson’s disease (PD). Oxidative stress occurs when the endogenous antioxidant systems are overcome by the generation of reactive oxygen species (ROS). A plausible source of oxidative stress...

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Detalles Bibliográficos
Autores principales: Belluzzi, Elisa, Bisaglia, Marco, Lazzarini, Elisabetta, Tabares, Leandro C., Beltramini, Mariano, Bubacco, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377658/
https://www.ncbi.nlm.nih.gov/pubmed/22723845
http://dx.doi.org/10.1371/journal.pone.0038026

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377658/
https://www.ncbi.nlm.nih.gov/pubmed/22723845
http://dx.doi.org/10.1371/journal.pone.0038026

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