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Paraoxonase-1 Is Not a Major Determinant of Stent Thrombosis in a Taiwanese Population

BACKGROUND: Clopidogrel is a prodrug that undergoes in vivo bioactivation to show its antiplatelet effects. Recent studies have shown that cytochrome P450 (CYP), ATP-binding cassette transporters (ABCB1), and paraoxonase-1 (PON1) play crucial roles in clopidogrel bioactivation. Here, we aim to deter...

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Detalles Bibliográficos
Autores principales:	Chen, Dong-Yi, Wang, Chao-Yung, Wen, Ming-Shien, Lee, Tsong-Hai, Chu, Yen, Hsieh, Ming-Jer, Chang, Shang-Hung, Lee, Cheng-Hung, Wang, Jian-Liang, Chen, Chun-Chi, Lu, Laing-Suei, Lee, Ming-Ta, Yeh, San-Jou, Lin, Fun-Chiung, Hsieh, I-Chang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377663/ https://www.ncbi.nlm.nih.gov/pubmed/22723959 http://dx.doi.org/10.1371/journal.pone.0039178

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