Cargando…
Characterization of Human DNA Polymerase Delta and Its Subassemblies Reconstituted by Expression in the Multibac System
Mammalian DNA polymerase δ (Pol δ), a four-subunit enzyme, plays a crucial and versatile role in DNA replication and DNA repair processes. We have reconstituted human Pol δ complexes in insect cells infected with a single baculovirus into which one or more subunits were assembled. This system allowe...
Autores principales: | Zhou, Yajing, Meng, Xiao, Zhang, Sufang, Lee, Ernest Y. C., Lee, Marietta Y. W. T. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377666/ https://www.ncbi.nlm.nih.gov/pubmed/22723953 http://dx.doi.org/10.1371/journal.pone.0039156 |
Ejemplares similares
-
P50, the Small Subunit of DNA Polymerase Delta, Is Required for Mediation of the Interaction of Polymerase Delta Subassemblies with PCNA
por: Wang, Yujue, et al.
Publicado: (2011) -
Production of Recombinant Human DNA Polymerase Delta in a Bombyx mori Bioreactor
por: Zhou, Yajing, et al.
Publicado: (2011) -
DNA polymerase delta interacting protein 3 facilitates the activation and maintenance of DNA damage checkpoint in response to replication stress
por: Zhang, Sufang, et al.
Publicado: (2022) -
DNA damage alters DNA polymerase δ to a form that exhibits increased discrimination against modified template bases and mismatched primers
por: Meng, Xiao, et al.
Publicado: (2009) -
Discovery of a novel DNA polymerase inhibitor and characterization of its antiproliferative properties
por: Mishra, Bhanvi, et al.
Publicado: (2018)