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Infection of RANKL-Primed RAW-D Macrophages with Porphyromonas gingivalis Promotes Osteoclastogenesis in a TNF-α-Independent Manner
Infection of macrophages with bacteria induces the production of pro-inflammatory cytokines including TNF-α. TNF-α directly stimulates osteoclast differentiation from bone marrow macrophages in vitro as well as indirectly via osteoblasts. Recently, it was reported that bacterial components such as L...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377672/ https://www.ncbi.nlm.nih.gov/pubmed/22723864 http://dx.doi.org/10.1371/journal.pone.0038500 |