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Age-Related Intraneuronal Elevation of αII-Spectrin Breakdown Product SBDP120 in Rodent Forebrain Accelerates in 3×Tg-AD Mice

Spectrins line the intracellular surface of plasmalemma and play a critical role in supporting cytoskeletal stability and flexibility. Spectrins can be proteolytically degraded by calpains and caspases, yielding breakdown products (SBDPs) of various molecular sizes, with SBDP120 being largely derive...

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Detalles Bibliográficos
Autores principales:	Cai, Yan, Zhu, Hai-Xia, Li, Jian-Ming, Luo, Xue-Gang, Patrylo, Peter R., Rose, Gregory M., Streeter, Jackson, Hayes, Ron, Wang, Kevin K. W., Yan, Xiao-Xin, Jeromin, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377681/ https://www.ncbi.nlm.nih.gov/pubmed/22723836 http://dx.doi.org/10.1371/journal.pone.0037599

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