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Differences in the Curing of [PSI(+)] Prion by Various Methods of Hsp104 Inactivation
[PSI (+)] yeast, containing the misfolded amyloid conformation of Sup35 prion, is cured by inactivation of Hsp104. There has been controversy as to whether inactivation of Hsp104 by guanidine treatment or by overexpression of the dominant negative Hsp104 mutant, Hsp104-2KT, cures [PSI (+)] by the sa...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377701/ https://www.ncbi.nlm.nih.gov/pubmed/22719845 http://dx.doi.org/10.1371/journal.pone.0037692 |