Autophagy in the Thymic Epithelium Is Dispensable for the Development of Self-Tolerance in a Novel Mouse Model

The thymic epithelium plays critical roles in the positive and negative selection of T cells. Recently, it was proposed that autophagy in thymic epithelial cells is essential for the induction of T cell tolerance to self antigens and thus for the prevention of autoimmune diseases. Here we have teste...

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Detalles Bibliográficos
Autores principales: Sukseree, Supawadee, Mildner, Michael, Rossiter, Heidemarie, Pammer, Johannes, Zhang, Cheng-Feng, Watanapokasin, Ramida, Tschachler, Erwin, Eckhart, Leopold
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377705/
https://www.ncbi.nlm.nih.gov/pubmed/22719991
http://dx.doi.org/10.1371/journal.pone.0038933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377705/
https://www.ncbi.nlm.nih.gov/pubmed/22719991
http://dx.doi.org/10.1371/journal.pone.0038933

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