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Autophagy in the Thymic Epithelium Is Dispensable for the Development of Self-Tolerance in a Novel Mouse Model
The thymic epithelium plays critical roles in the positive and negative selection of T cells. Recently, it was proposed that autophagy in thymic epithelial cells is essential for the induction of T cell tolerance to self antigens and thus for the prevention of autoimmune diseases. Here we have teste...
Autores principales: | Sukseree, Supawadee, Mildner, Michael, Rossiter, Heidemarie, Pammer, Johannes, Zhang, Cheng-Feng, Watanapokasin, Ramida, Tschachler, Erwin, Eckhart, Leopold |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3377705/ https://www.ncbi.nlm.nih.gov/pubmed/22719991 http://dx.doi.org/10.1371/journal.pone.0038933 |
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