Awaking stem cells from dormancy: growing old and fighting cancer

It is generally accepted that a distinguishing property of stem cells (SCs), as compared to their more differentiated progenitors, is that of infrequent division, often referred to as ‘quiescence’. As regards hematopoietic stem cells (HSC), their resistance to antiproliferative drugs supports this n...

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Detalles Bibliográficos
Autores principales: Viale, Andrea, Pelicci, Pier G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378114/
https://www.ncbi.nlm.nih.gov/pubmed/20049708
http://dx.doi.org/10.1002/emmm.200900019
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author Viale, Andrea
Pelicci, Pier G
author_facet Viale, Andrea
Pelicci, Pier G
author_sort Viale, Andrea
collection PubMed
description It is generally accepted that a distinguishing property of stem cells (SCs), as compared to their more differentiated progenitors, is that of infrequent division, often referred to as ‘quiescence’. As regards hematopoietic stem cells (HSC), their resistance to antiproliferative drugs supports this notion. Maintenance of quiescence is thought to be critical for the preservation of HSCs' function.
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spelling pubmed-33781142012-09-17 Awaking stem cells from dormancy: growing old and fighting cancer Viale, Andrea Pelicci, Pier G EMBO Mol Med Closeup It is generally accepted that a distinguishing property of stem cells (SCs), as compared to their more differentiated progenitors, is that of infrequent division, often referred to as ‘quiescence’. As regards hematopoietic stem cells (HSC), their resistance to antiproliferative drugs supports this notion. Maintenance of quiescence is thought to be critical for the preservation of HSCs' function. WILEY-VCH Verlag 2009-05 /pmc/articles/PMC3378114/ /pubmed/20049708 http://dx.doi.org/10.1002/emmm.200900019 Text en Copyright © 2009 EMBO Molecular Medicine
spellingShingle Closeup
Viale, Andrea
Pelicci, Pier G
Awaking stem cells from dormancy: growing old and fighting cancer
title Awaking stem cells from dormancy: growing old and fighting cancer
title_full Awaking stem cells from dormancy: growing old and fighting cancer
title_fullStr Awaking stem cells from dormancy: growing old and fighting cancer
title_full_unstemmed Awaking stem cells from dormancy: growing old and fighting cancer
title_short Awaking stem cells from dormancy: growing old and fighting cancer
title_sort awaking stem cells from dormancy: growing old and fighting cancer
topic Closeup
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378114/
https://www.ncbi.nlm.nih.gov/pubmed/20049708
http://dx.doi.org/10.1002/emmm.200900019
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AT peliccipierg awakingstemcellsfromdormancygrowingoldandfightingcancer

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