The 28-amino acid form of an APLP1-derived Aβ-like peptide is a surrogate marker for Aβ42 production in the central nervous system

Surrogate markers for the Alzheimer disease (AD)-associated 42-amino acid form of amyloid-β (Aβ42) have been sought because they may aid in the diagnosis of AD and for clarification of disease pathogenesis. Here, we demonstrate that human cerebrospinal fluid (CSF) contains three APLP1-derived Aβ-lik...

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Detalles Bibliográficos
Autores principales: Yanagida, Kanta, Okochi, Masayasu, Tagami, Shinji, Nakayama, Taisuke, Kodama, Takashi S, Nishitomi, Kouhei, Jiang, Jingwei, Mori, Kohji, Tatsumi, Shin-ichi, Arai, Tetsuaki, Ikeuchi, Takeshi, Kasuga, Kensaku, Tokuda, Takahiko, Kondo, Masaki, Ikeda, Masaki, Deguchi, Kentaro, Kazui, Hiroaki, Tanaka, Toshihisa, Morihara, Takashi, Hashimoto, Ryota, Kudo, Takashi, Steiner, Harald, Haass, Christian, Tsuchiya, Kuniaki, Akiyama, Haruhiko, Kuwano, Ryozo, Takeda, Masatoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378133/
https://www.ncbi.nlm.nih.gov/pubmed/20049724
http://dx.doi.org/10.1002/emmm.200900026

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