Hedgehog signalling in colon cancer and stem cells

The participation of the HH pathway in colon cancer has remained controversial. In this issue, Varnat et al (2009) demonstrate that HH signalling is essential for human colon cancer growth, recurrence, metastases and stem cell expansion. This closeup by Gulino et al discusses the paper and its impli...

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Detalles Bibliográficos
Autores principales: Gulino, Alberto, Ferretti, Elisabetta, De Smaele, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
Closeup
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378148/
https://www.ncbi.nlm.nih.gov/pubmed/20049733
http://dx.doi.org/10.1002/emmm.200900042
Descripción
Sumario:The participation of the HH pathway in colon cancer has remained controversial. In this issue, Varnat et al (2009) demonstrate that HH signalling is essential for human colon cancer growth, recurrence, metastases and stem cell expansion. This closeup by Gulino et al discusses the paper and its implications.

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