Hedgehog signalling in colon cancer and stem cells

The participation of the HH pathway in colon cancer has remained controversial. In this issue, Varnat et al (2009) demonstrate that HH signalling is essential for human colon cancer growth, recurrence, metastases and stem cell expansion. This closeup by Gulino et al discusses the paper and its impli...

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Autores principales: Gulino, Alberto, Ferretti, Elisabetta, De Smaele, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378148/
https://www.ncbi.nlm.nih.gov/pubmed/20049733
http://dx.doi.org/10.1002/emmm.200900042
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author Gulino, Alberto
Ferretti, Elisabetta
De Smaele, Enrico
author_facet Gulino, Alberto
Ferretti, Elisabetta
De Smaele, Enrico
author_sort Gulino, Alberto
collection PubMed
description The participation of the HH pathway in colon cancer has remained controversial. In this issue, Varnat et al (2009) demonstrate that HH signalling is essential for human colon cancer growth, recurrence, metastases and stem cell expansion. This closeup by Gulino et al discusses the paper and its implications.
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spelling pubmed-33781482012-09-17 Hedgehog signalling in colon cancer and stem cells Gulino, Alberto Ferretti, Elisabetta De Smaele, Enrico EMBO Mol Med Closeup The participation of the HH pathway in colon cancer has remained controversial. In this issue, Varnat et al (2009) demonstrate that HH signalling is essential for human colon cancer growth, recurrence, metastases and stem cell expansion. This closeup by Gulino et al discusses the paper and its implications. WILEY-VCH Verlag 2009-09 /pmc/articles/PMC3378148/ /pubmed/20049733 http://dx.doi.org/10.1002/emmm.200900042 Text en Copyright © 2009 EMBO Molecular Medicine
spellingShingle Closeup
Gulino, Alberto
Ferretti, Elisabetta
De Smaele, Enrico
Hedgehog signalling in colon cancer and stem cells
title Hedgehog signalling in colon cancer and stem cells
title_full Hedgehog signalling in colon cancer and stem cells
title_fullStr Hedgehog signalling in colon cancer and stem cells
title_full_unstemmed Hedgehog signalling in colon cancer and stem cells
title_short Hedgehog signalling in colon cancer and stem cells
title_sort hedgehog signalling in colon cancer and stem cells
topic Closeup
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378148/
https://www.ncbi.nlm.nih.gov/pubmed/20049733
http://dx.doi.org/10.1002/emmm.200900042
work_keys_str_mv AT gulinoalberto hedgehogsignallingincoloncancerandstemcells
AT ferrettielisabetta hedgehogsignallingincoloncancerandstemcells
AT desmaeleenrico hedgehogsignallingincoloncancerandstemcells

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