Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases

Patients affected by mitochondrial OXPHOS disorders are still faced with a grim lack of therapeutic options. In this Closeup, Carlos Moraes revisits the recent data by Giovanni Manfredi on PKA's functions in the mitochondria and now its modulation can improve respiration and ATP production in C...

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Detalles Bibliográficos
Autor principal: Moraes, Carlos T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2009
Materias:
Closeup
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378150/
https://www.ncbi.nlm.nih.gov/pubmed/20049740
http://dx.doi.org/10.1002/emmm.200900049
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author Moraes, Carlos T
author_facet Moraes, Carlos T
author_sort Moraes, Carlos T
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description Patients affected by mitochondrial OXPHOS disorders are still faced with a grim lack of therapeutic options. In this Closeup, Carlos Moraes revisits the recent data by Giovanni Manfredi on PKA's functions in the mitochondria and now its modulation can improve respiration and ATP production in COX-defective cells.
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spelling pubmed-33781502012-09-17 Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases Moraes, Carlos T EMBO Mol Med Closeup Patients affected by mitochondrial OXPHOS disorders are still faced with a grim lack of therapeutic options. In this Closeup, Carlos Moraes revisits the recent data by Giovanni Manfredi on PKA's functions in the mitochondria and now its modulation can improve respiration and ATP production in COX-defective cells. WILEY-VCH Verlag 2009-11 /pmc/articles/PMC3378150/ /pubmed/20049740 http://dx.doi.org/10.1002/emmm.200900049 Text en Copyright © 2009 EMBO Molecular Medicine
spellingShingle Closeup
Moraes, Carlos T
Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases
title Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases
title_full Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases
title_fullStr Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases
title_full_unstemmed Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases
title_short Making the most of what you've got: Optimizing residual OXPHOS function in mitochondrial diseases
title_sort making the most of what you've got: optimizing residual oxphos function in mitochondrial diseases
topic Closeup
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378150/
https://www.ncbi.nlm.nih.gov/pubmed/20049740
http://dx.doi.org/10.1002/emmm.200900049
work_keys_str_mv AT moraescarlost makingthemostofwhatyouvegotoptimizingresidualoxphosfunctioninmitochondrialdiseases

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