Dendritic cell functional improvement in a preclinical model of lentiviral-mediated gene therapy for Wiskott-Aldrich syndrome

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency caused by the defective expression of the WAS protein (WASP) in hematopoietic cells. It has been shown that dendritic cells (DCs) are functionally impaired in WAS patients and was(−/−) mice. We have previously demonstrated th...

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Detalles Bibliográficos
Autores principales: Catucci, Marco, Prete, Francesca, Bosticardo, Marita, Castiello, Maria Carmina, Draghici, Elena, Locci, Michela, Roncarolo, Maria Grazia, Aiuti, Alessandro, Benvenuti, Federica, Villa, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378501/
https://www.ncbi.nlm.nih.gov/pubmed/22189416
http://dx.doi.org/10.1038/gt.2011.202

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