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Structural and functional conservation of key domains in InsP(3) and ryanodine receptors

Inositol 1,4,5-trisphosphate receptors (InsP(3)R) and ryanodine receptors (RyR) are tetrameric intracellular Ca(2+) channels(1). For each, the pore is formed by C-terminal transmembrane domains and regulated by signals detected by the large cytosolic structures. InsP(3)R gating is initiated by InsP(...

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Detalles Bibliográficos
Autores principales:	Seo, Min-Duk, Velamakanni, Saroj, Ishiyama, Noboru, Stathopulos, Peter B., Rossi, Ana M., Khan, Samir A., Dale, Philippa, Li, Congmin, Ames, James B., Ikura, Mitsuhiko, Taylor, Colin W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378505/ https://www.ncbi.nlm.nih.gov/pubmed/22286060 http://dx.doi.org/10.1038/nature10751

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