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Sequential genetic change at the TP53 and chemokine receptor CXCR4 locus during transformation of human ovarian surface epithelium

Early genetic events in the development of high-grade serous ovarian cancer, HGSOC, may define the molecular basis of the profound structural and numerical instability of chromosomes in this disease. To discover candidate genetic changes we sequentially passaged cells from a karyotypically normal hT...

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Detalles Bibliográficos
Autores principales:	Archibald, Kyra M, Kulbe, Hagen, Kwong, Joseph, Chakravarty, Probir, Temple, Jill, Chaplin, Tracy, Flak, Magdalena B, McNeish, Iain A, Deen, Suha, Brenton, James D, Young, Bryan D, Balkwill, Frances
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378508/ https://www.ncbi.nlm.nih.gov/pubmed/22266861 http://dx.doi.org/10.1038/onc.2011.653

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