Cargando…

Interaction of Protein C Inhibitor with the Type II Transmembrane Serine Protease Enteropeptidase

The serine protease inhibitor protein C inhibitor (PCI) is expressed in many human tissues and exhibits broad protease reactivity. PCI binds glycosaminoglycans and certain phospholipids, which modulate its inhibitory activity. Enteropeptidase (EP) is a type II transmembrane serine protease mainly fo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Prohaska, Thomas A., Wahlmüller, Felix C., Furtmüller, Margareta, Geiger, Margarethe
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378520/ https://www.ncbi.nlm.nih.gov/pubmed/22723979 http://dx.doi.org/10.1371/journal.pone.0039262

Ejemplares similares

A+-Helix of Protein C Inhibitor (PCI) Is a Cell-penetrating Peptide That Mediates Cell Membrane Permeation of PCI
por: Yang, Hanjiang, et al.
Publicado: (2015)

Type II Transmembrane Serine Protease Gene Variants Associate with Breast Cancer
por: Luostari, Kaisa, et al.
Publicado: (2014)

Evolutionary history of type II transmembrane serine proteases involved in viral priming
por: Forni, Diego, et al.
Publicado: (2022)

Type II Transmembrane Serine Proteases as Modulators in Adipose Tissue Phenotype and Function
por: Wu, Qingyu, et al.
Publicado: (2023)

Phospholipid Binding Protein C Inhibitor (PCI) Is Present on Microparticles Generated In Vitro and In Vivo
por: Einfinger, Katrin, et al.
Publicado: (2015)

Docking study of transmembrane serine protease type 2 inhibitors for the treatment of COVID-19
por: Solanki, Naishadh
Publicado: (2022)

Dysregulation of Type II Transmembrane Serine Proteases and Ligand-Dependent Activation of MET in Urological Cancers
por: Mukai, Shoichiro, et al.
Publicado: (2020)

TMPRSS4, a type II transmembrane serine protease, as a potential therapeutic target in cancer
por: Kim, Semi
Publicado: (2023)

Discovery and characterization of a small‐molecule enteropeptidase inhibitor, SCO‐792
por: Sasaki, Masako, et al.
Publicado: (2019)

Potential Simultaneous Inhibitors of Angiotensin-Converting Enzyme 2 and Transmembrane Protease, Serine 2
por: Wu, Ching-Yuan, et al.
Publicado: (2020)

An Exploratory Randomized Trial of SCO-792, an Enteropeptidase Inhibitor, in Patients With Type 2 Diabetes and Albuminuria
por: Kagawa, Tomoya, et al.
Publicado: (2022)

SCO‐792, an enteropeptidase inhibitor, improves disease status of diabetes and obesity in mice
por: Yashiro, Hiroaki, et al.
Publicado: (2019)

The Global Status and Trends of Enteropeptidase: A Bibliometric Study
por: Yang, Xiaoli, et al.
Publicado: (2022)

Transmembrane serine protease 2 is a prognostic factor for lung adenocarcinoma
por: Schneider, Marc A., et al.
Publicado: (2022)

Cleavage Specificity Analysis of Six Type II Transmembrane Serine Proteases (TTSPs) Using PICS with Proteome-Derived Peptide Libraries
por: Barré, Olivier, et al.
Publicado: (2014)

Structure basis for the unique specificity of medaka enteropeptidase light chain
por: Xu, Jin, et al.
Publicado: (2014)

Antithrombin controls tumor migration, invasion and angiogenesis by inhibition of enteropeptidase
por: Luengo-Gil, Ginés, et al.
Publicado: (2016)

Activation of Human Pancreatic Proteolytic Enzymes: The Role of Enteropeptidase and Trypsin
por: Freiburghaus, Andreas U., et al.
Publicado: (2021)

Intracellular autoactivation of TMPRSS11A, an airway epithelial transmembrane serine protease
por: Zhang, Ce, et al.
Publicado: (2020)

Magnesium treatment on methylation changes of transmembrane serine protease 2 (TMPRSS2)
por: Fan, Lei, et al.
Publicado: (2021)

Association of the Transmembrane Serine Protease-2 (TMPRSS2) Polymorphisms with COVID-19
por: Posadas-Sánchez, Rosalinda, et al.
Publicado: (2022)

The Proteolytic Activation of (H3N2) Influenza A Virus Hemagglutinin Is Facilitated by Different Type II Transmembrane Serine Proteases
por: Kühn, Nora, et al.
Publicado: (2016)

The role of Serine Proteases and Serine Protease Inhibitors in the migration of Gonadotropin-Releasing Hormone neurons
por: Drapkin, Paola T, et al.
Publicado: (2002)

Identification of novel transmembrane Protease Serine Type 2 drug candidates for COVID-19 using computational studies
por: Elbadwi, Fatima A., et al.
Publicado: (2021)

Role of SCO-792, A Novel Enteropeptidase Inhibitor, In the Prevention of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis
por: Rashid, Mohammed Y, et al.
Publicado: (2021)

In-silico screening for identification of potential inhibitors against SARS-CoV-2 transmembrane serine protease 2 (TMPRSS2)
por: Barge, Sagar, et al.
Publicado: (2021)

Pharmacoinformatics-based identification of transmembrane protease serine-2 inhibitors from Morus Alba as SARS-CoV-2 cell entry inhibitors
por: Shakya, Anshul, et al.
Publicado: (2021)

Cryo-EM structures reveal the activation and substrate recognition mechanism of human enteropeptidase
por: Yang, Xiaoli, et al.
Publicado: (2022)

Unexpected Activity of a Novel Kunitz-type Inhibitor: INHIBITION OF CYSTEINE PROTEASES BUT NOT SERINE PROTEASES
por: Smith, David, et al.
Publicado: (2016)

Diarylethene‐Based Photoswitchable Inhibitors of Serine Proteases
por: Babii, Oleg, et al.
Publicado: (2021)

Editorial: Serine protease inhibitors and their therapeutic applications
por: Crocetti, Letizia, et al.
Publicado: (2022)

Virtual Screening of Natural Products against Type II Transmembrane Serine Protease (TMPRSS2), the Priming Agent of Coronavirus 2 (SARS-CoV-2)
por: Rahman, Noor, et al.
Publicado: (2020)

The human Transmembrane Protease Serine 2 is necessary for the production of Group 2 influenza A virus pseudotypes
por: Ferrara, Francesca, et al.
Publicado: (2013)

Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A
por: Wang, Hongge, et al.
Publicado: (2019)

rs12329760 Polymorphism in Transmembrane Serine Protease 2 Gene and Risk of Coronavirus Disease 2019 Mortality
por: Beheshti Shirazi, Saeedeh Sadat, et al.
Publicado: (2022)

Impacts of transmembrane serine protease 4 expression on susceptibility to severe acute respiratory syndrome coronavirus 2
por: Tan, Qi, et al.
Publicado: (2023)

The under‐appreciated world of the serpin family of serine proteinase inhibitors
por: Bouton, Marie‐Christine, et al.
Publicado: (2023)

Enteropeptidase inhibition improves kidney function in a rat model of diabetic kidney disease
por: Sugama, Jun, et al.
Publicado: (2020)

Computational screening of phytochemicals from three medicinal plants as inhibitors of transmembrane protease serine 2 implicated in SARS-CoV-2 infection
por: Oyedara, Omotayo O., et al.
Publicado: (2021)

Hybrid drug-screening strategy identifies potential SARS-CoV-2 cell-entry inhibitors targeting human transmembrane serine protease
por: Feng, Yufei, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mlbkdu6f9inubltdaognto6lk0