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Structural Constraints Identified with Covariation Analysis in Ribosomal RNA
Covariation analysis is used to identify those positions with similar patterns of sequence variation in an alignment of RNA sequences. These constraints on the evolution of two positions are usually associated with a base pair in a helix. While mutual information (MI) has been used to accurately pre...
Autores principales: | Shang, Lei, Xu, Weijia, Ozer, Stuart, Gutell, Robin R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378556/ https://www.ncbi.nlm.nih.gov/pubmed/22724009 http://dx.doi.org/10.1371/journal.pone.0039383 |
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