Cargando…

Circadian-Related Heteromerization of Adrenergic and Dopamine D(4) Receptors Modulates Melatonin Synthesis and Release in the Pineal Gland

The role of the pineal gland is to translate the rhythmic cycles of night and day encoded by the retina into hormonal signals that are transmitted to the rest of the neuronal system in the form of serotonin and melatonin synthesis and release. Here we describe that the production of both melatonin a...

Descripción completa

Detalles Bibliográficos
Autores principales:	González, Sergio, Moreno-Delgado, David, Moreno, Estefanía, Pérez-Capote, Kamil, Franco, Rafael, Mallol, Josefa, Cortés, Antoni, Casadó, Vicent, Lluís, Carme, Ortiz, Jordi, Ferré, Sergi, Canela, Enric, McCormick, Peter J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378626/ https://www.ncbi.nlm.nih.gov/pubmed/22723743 http://dx.doi.org/10.1371/journal.pbio.1001347

Ejemplares similares

Molecular Evidence of Adenosine Deaminase Linking Adenosine A(2A) Receptor and CD26 Proteins
por: Moreno, Estefanía, et al.
Publicado: (2018)

Significant Functional Differences Between Dopamine D(4) Receptor Polymorphic Variants Upon Heteromerization with α(1A) Adrenoreceptors
por: Homar-Ruano, Patricia, et al.
Publicado: (2023)

Basic Concepts in G-Protein-Coupled Receptor Homo- and Heterodimerization
por: Franco, Rafael, et al.
Publicado: (2007)

Cross-communication between G(i) and G(s) in a G-protein-coupled receptor heterotetramer guided by a receptor C-terminal domain
por: Navarro, Gemma, et al.
Publicado: (2018)

Cocaine Inhibits Dopamine D(2) Receptor Signaling via Sigma-1-D(2) Receptor Heteromers
por: Navarro, Gemma, et al.
Publicado: (2013)

Evidence for functional pre-coupled complexes of receptor heteromers and adenylyl cyclase
por: Navarro, Gemma, et al.
Publicado: (2018)

Quaternary structure of a G-protein-coupled receptor heterotetramer in complex with G(i) and G(s)
por: Navarro, Gemma, et al.
Publicado: (2016)

Detection of Heteromers Formed by Cannabinoid CB(1), Dopamine D(2), and Adenosine A(2A) G-Protein-Coupled Receptors by Combining Bimolecular Fluorescence Complementation and Bioluminescence Energy Transfer
por: Navarro, Gemma, et al.
Publicado: (2008)

Modulation of dopamine D(1) receptors via histamine H(3) receptors is a novel therapeutic target for Huntington's disease
por: Moreno-Delgado, David, et al.
Publicado: (2020)

Adenosine A(2A) Receptors and A(2A) Receptor Heteromers as Key Players in Striatal Function
por: Ferré, Sergi, et al.
Publicado: (2011)

The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet?
por: Moreno, Estefanía, et al.
Publicado: (2019)

Striatal Pre- and Postsynaptic Profile of Adenosine A(2A) Receptor Antagonists
por: Orru, Marco, et al.
Publicado: (2011)

Melatonin formation in rat pineal gland organ culture: induction by an adrenergic beta 2-stimulating drug.
por: Bäckström, M., et al.
Publicado: (1973)

Heteromerization of G-Protein–Coupled Receptors. Implications for Central Nervous System Function and Dysfunction
por: Ferré, Sergi
Publicado: (2007)

Pineal Calcification, Melatonin Production, Aging, Associated Health Consequences and Rejuvenation of the Pineal Gland
por: Tan, Dun Xian, et al.
Publicado: (2018)

Possible Role of Pineal and Extra-Pineal Melatonin in Surveillance, Immunity, and First-Line Defense
por: Markus, Regina P., et al.
Publicado: (2021)

Melatonin: Miracles far beyond the pineal gland
por: Afzal, Rafia
Publicado: (2012)

The pineal gland: A model for adrenergic modulation of ubiquitin ligases
por: Vriend, Jerry, et al.
Publicado: (2017)

Pineal melatonin is a circadian time-giver for leptin rhythm in Syrian hamsters
por: Chakir, Ibtissam, et al.
Publicado: (2015)

The reno-pineal axis: A novel role for melatonin
por: Kalra, Sanjay, et al.
Publicado: (2012)

Adrenergic Activation of Melatonin Secretion in Ovine Pineal Explants in Short-Term Superfusion Culture Occurs via Protein Synthesis Independent and Dependent Phenomena
por: Lewczuk, Bogdan, et al.
Publicado: (2014)

Functional Fine-Tuning of Metabolic Pathways by the Endocannabinoid System—Implications for Health and Disease
por: Moreno, Estefanía, et al.
Publicado: (2021)

The Mystery behind the Pineal Gland: Melatonin Affects the Metabolism of Cholesterol
por: Karolczak, Kamil, et al.
Publicado: (2019)

Pineal hormone melatonin as an adjuvant treatment for COVID-19 (Review)
por: Vlachou, Marilena, et al.
Publicado: (2021)

A brief review about melatonin, a pineal hormone
por: do Amaral, Fernanda Gaspar, et al.
Publicado: (2018)

Dopamine D(4) receptor, but not the ADHD-associated D(4.7) variant, forms functional heteromers with the dopamine D(2S) receptor in the brain
por: González, Sergio, et al.
Publicado: (2011)

Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB(1) and Serotonin 5-HT(2A) Receptors
por: Viñals, Xavier, et al.
Publicado: (2015)

The Interplay between Cancer Biology and the Endocannabinoid System—Significance for Cancer Risk, Prognosis and Response to Treatment
por: Moreno, Estefanía, et al.
Publicado: (2020)

Nk3R blockade has sex-divergent effects on memory in mice
por: Florido, Antonio, et al.
Publicado: (2022)

Complexes of Ghrelin GHS-R1a, GHS-R1b, and Dopamine D(1) Receptors Localized in the Ventral Tegmental Area as Main Mediators of the Dopaminergic Effects of Ghrelin
por: Navarro, Gemma, et al.
Publicado: (2022)

Relationship between nocturnal serotonin surge and melatonin onset in rodent pineal gland
por: Liu, Tiecheng, et al.
Publicado: (2006)

Leptin Modulates Norepinephrine-Mediated Melatonin Synthesis in Cultured Rat Pineal Gland
por: Peliciari-Garcia, Rodrigo Antonio, et al.
Publicado: (2013)

Morning Plasma Melatonin Differences in Autism: Beyond the Impact of Pineal Gland Volume
por: Maruani, Anna, et al.
Publicado: (2019)

Singular Location and Signaling Profile of Adenosine A(2A)-Cannabinoid CB(1) Receptor Heteromers in the Dorsal Striatum
por: Moreno, Estefanía, et al.
Publicado: (2018)

Diurnal Profiles of Melatonin Synthesis-Related Indoles, Catecholamines and Their Metabolites in the Duck Pineal Organ
por: Lewczuk, Bogdan, et al.
Publicado: (2014)

Regulation of bone mass through pineal‐derived melatonin‐MT2 receptor pathway
por: Sharan, Kunal, et al.
Publicado: (2017)

Adenosine Deaminase Enhances the Immunogenicity of Human Dendritic Cells from Healthy and HIV-Infected Individuals
por: Casanova, Víctor, et al.
Publicado: (2012)

Decreased striatal adenosine A(2A)-dopamine D(2) receptor heteromerization in schizophrenia
por: Valle-León, Marta, et al.
Publicado: (2020)

Interleukin-1β Modulates Melatonin Secretion in Ovine Pineal Gland: Ex Vivo Study
por: Herman, A. P., et al.
Publicado: (2015)

Rumen-Protected 5-Hydroxytryptophan Improves Sheep Melatonin Synthesis in the Pineal Gland and Intestinal Tract
por: Zhao, Fang, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_447mjpmi2l2a6tkgfpncccomvl