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A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71
Enterovirus 71 (EV71), a major agent of hand-foot-and-mouth disease in children, can cause severe central nervous system disease and mortality. At present no vaccine or antiviral therapy is available. We have determined high-resolution structures for the mature virus and natural empty particles. The...
Autores principales: | Wang, Xiangxi, Peng, Wei, Ren, Jingshan, Hu, Zhongyu, Xu, Jiwei, Lou, Zhiyong, Li, Xumei, Yin, Weidong, Shen, Xinliang, Porta, Claudine, Walter, Thomas S., Evans, Gwyndaf, Axford, Danny, Owen, Robin, Rowlands, David J., Wang, Junzhi, Stuart, David I., Fry, Elizabeth E., Rao, Zihe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378640/ https://www.ncbi.nlm.nih.gov/pubmed/22388738 http://dx.doi.org/10.1038/nsmb.2255 |
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