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Genomic evidence of pre-invasive clonal expansion, dispersal and progression in bronchial dysplasia
The term ‘field cancerization’ is used to describe an epithelial surface that has a propensity to develop cancerous lesions, and in the case of the aerodigestive tract this is often as a result of chronic exposure to carcinogens in cigarette smoke 1, 2. The clinical endpoint is the development of mu...
Autores principales: | McCaughan, Frank, Pipinikas, Christodoulos P, Janes, Sam M, George, P Jeremy, Rabbitts, Pamela H, Dear, Paul H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Ltd.
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378694/ https://www.ncbi.nlm.nih.gov/pubmed/21506132 http://dx.doi.org/10.1002/path.2887 |
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