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α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system

The source of Parkinson disease-linked α-synuclein (aSyn) in human cerebrospinal fluid (CSF) remains unknown. We decided to measure the concentration of aSyn and its gradient in human CSF specimens and compared it with serum to explore its origin. We correlated aSyn concentrations in CSF versus seru...

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Detalles Bibliográficos
Autores principales:	Mollenhauer, Brit, Trautmann, Ellen, Otte, Birgit, Ng, Juliana, Spreer, Annette, Lange, Peter, Sixel-Döring, Friederike, Hakimi, Mansoureh, VonSattel, Jean-Paul, Nussbaum, Robert, Trenkwalder, Claudia, Schlossmacher, Michael G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Vienna 2012
Materias:	Basic Neurosciences, Genetics and Immunology - Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378837/ https://www.ncbi.nlm.nih.gov/pubmed/22426833 http://dx.doi.org/10.1007/s00702-012-0784-0

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