DNMT1 modulates gene expression without its catalytic activity partially through its interactions with histone-modifying enzymes

While DNA methyltransferase1 (DNMT1) is classically known for its functions as a maintenance methyltransferase enzyme, additional roles for DNMT1 in gene expression are not as clearly understood. Several groups have shown that deletion of the catalytic domain from DNMT1 does not abolish repressive a...

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Detalles Bibliográficos
Autores principales: Clements, Eriko G., Mohammad, Helai P., Leadem, Benjamin R., Easwaran, Hariharan, Cai, Yi, Van Neste, Leander, Baylin, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Gene Regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378872/
https://www.ncbi.nlm.nih.gov/pubmed/22278882
http://dx.doi.org/10.1093/nar/gks031

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