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CUX1 transcription factor is required for optimal ATM/ATR-mediated responses to DNA damage

The p110 Cut homeobox 1 (CUX1) transcription factor regulates genes involved in DNA replication and chromosome segregation. Using a genome-wide-approach, we now demonstrate that CUX1 also modulates the constitutive expression of DNA damage response genes, including ones encoding ATM and ATR, as well...

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Detalles Bibliográficos
Autores principales:	Vadnais, Charles, Davoudi, Sayeh, Afshin, Mojdeh, Harada, Ryoko, Dudley, Rachel, Clermont, Pier-Luc, Drobetsky, Elliot, Nepveu, Alain
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378881/ https://www.ncbi.nlm.nih.gov/pubmed/22319212 http://dx.doi.org/10.1093/nar/gks041

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