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Prebiotically plausible mechanisms increase compositional diversity of nucleic acid sequences

During the origin of life, the biological information of nucleic acid polymers must have increased to encode functional molecules (the RNA world). Ribozymes tend to be compositionally unbiased, as is the vast majority of possible sequence space. However, ribonucleotides vary greatly in synthetic yie...

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Detalles Bibliográficos
Autores principales: Derr, Julien, Manapat, Michael L., Rajamani, Sudha, Leu, Kevin, Xulvi-Brunet, Ramon, Joseph, Isaac, Nowak, Martin A., Chen, Irene A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378899/
https://www.ncbi.nlm.nih.gov/pubmed/22319215
http://dx.doi.org/10.1093/nar/gks065