Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease

Coronary heart disease (CHD) is the leading causes of morbidity and mortality in China. The diagnosis of CHD in Traditional Chinese Medicine (TCM) was mainly based on experience in the past. In this paper, we proposed four MI-based association algorithms to analyze phenotype networks of CHD, and est...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Jianxin, Lu, Peng, Zuo, Xiaohan, Shi, Qi, Zhao, Huihui, Luo, Liangtao, Yi, Jianqiang, Zheng, Chenglong, Yang, Yi, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378973/
https://www.ncbi.nlm.nih.gov/pubmed/23002393
http://dx.doi.org/10.1155/2012/546230
_version_ 1782236111712550912
author Chen, Jianxin
Lu, Peng
Zuo, Xiaohan
Shi, Qi
Zhao, Huihui
Luo, Liangtao
Yi, Jianqiang
Zheng, Chenglong
Yang, Yi
Wang, Wei
author_facet Chen, Jianxin
Lu, Peng
Zuo, Xiaohan
Shi, Qi
Zhao, Huihui
Luo, Liangtao
Yi, Jianqiang
Zheng, Chenglong
Yang, Yi
Wang, Wei
author_sort Chen, Jianxin
collection PubMed
description Coronary heart disease (CHD) is the leading causes of morbidity and mortality in China. The diagnosis of CHD in Traditional Chinese Medicine (TCM) was mainly based on experience in the past. In this paper, we proposed four MI-based association algorithms to analyze phenotype networks of CHD, and established scale of syndromes to automatically generate the diagnosis of patients based on their phenotypes. We also compared the change of core syndromes that CHD were combined with other diseases, and presented the different phenotype spectra.
format Online
Article
Text
id pubmed-3378973
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-33789732012-09-21 Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease Chen, Jianxin Lu, Peng Zuo, Xiaohan Shi, Qi Zhao, Huihui Luo, Liangtao Yi, Jianqiang Zheng, Chenglong Yang, Yi Wang, Wei Evid Based Complement Alternat Med Research Article Coronary heart disease (CHD) is the leading causes of morbidity and mortality in China. The diagnosis of CHD in Traditional Chinese Medicine (TCM) was mainly based on experience in the past. In this paper, we proposed four MI-based association algorithms to analyze phenotype networks of CHD, and established scale of syndromes to automatically generate the diagnosis of patients based on their phenotypes. We also compared the change of core syndromes that CHD were combined with other diseases, and presented the different phenotype spectra. Hindawi Publishing Corporation 2012 2012-06-12 /pmc/articles/PMC3378973/ /pubmed/23002393 http://dx.doi.org/10.1155/2012/546230 Text en Copyright © 2012 Jianxin Chen et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Chen, Jianxin
Lu, Peng
Zuo, Xiaohan
Shi, Qi
Zhao, Huihui
Luo, Liangtao
Yi, Jianqiang
Zheng, Chenglong
Yang, Yi
Wang, Wei
Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease
title Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease
title_full Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease
title_fullStr Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease
title_full_unstemmed Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease
title_short Clinical Data Mining of Phenotypic Network in Angina Pectoris of Coronary Heart Disease
title_sort clinical data mining of phenotypic network in angina pectoris of coronary heart disease
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378973/
https://www.ncbi.nlm.nih.gov/pubmed/23002393
http://dx.doi.org/10.1155/2012/546230
work_keys_str_mv AT chenjianxin clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT lupeng clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT zuoxiaohan clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT shiqi clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT zhaohuihui clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT luoliangtao clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT yijianqiang clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT zhengchenglong clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT yangyi clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease
AT wangwei clinicaldataminingofphenotypicnetworkinanginapectorisofcoronaryheartdisease

Ejemplares similares