Cargando…

Prediction of 492 human protein kinase substrate specificities

BACKGROUND: Complex intracellular signaling networks monitor diverse environmental inputs to evoke appropriate and coordinated effector responses. Defective signal transduction underlies many pathologies, including cancer, diabetes, autoimmunity and about 400 other human diseases. Therefore, there i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Safaei, Javad, Maňuch, Ján, Gupta, Arvind, Stacho, Ladislav, Pelech, Steven
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Proceedings
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379035/ https://www.ncbi.nlm.nih.gov/pubmed/22165948 http://dx.doi.org/10.1186/1477-5956-9-S1-S6

Ejemplares similares

Linearization of ancestral multichromosomal genomes
por: Maňuch, Ján, et al.
Publicado: (2012)

SVM-based prediction of caspase substrate cleavage sites
por: Wee, Lawrence JK, et al.
Publicado: (2006)

Protein kinase C and human uterine contractility
por: Eude-Le Parco, Isabelle, et al.
Publicado: (2007)

Dimerization in protein kinase signaling
por: Pelech, Steven
Publicado: (2006)

Prediction of dinucleotide-specific RNA-binding sites in proteins
por: Fernandez, Michael, et al.
Publicado: (2011)

Prioritization of pathogenic mutations in the protein kinase superfamily
por: Izarzugaza, Jose MG, et al.
Publicado: (2012)

Using multitask classification methods to investigate the kinase-specific phosphorylation sites
por: Gao, Shan, et al.
Publicado: (2012)

In silico engineering of aggregation-prone recombinant proteins for substrate recognition by the chaperonin GroEL
por: Kumar, Vipul, et al.
Publicado: (2012)

Whole-Genome Sequence of the Microcin E492-Producing Strain Klebsiella pneumoniae RYC492
por: Marcoleta, Andrés, et al.
Publicado: (2013)

Signal transduction in neurons: effects of cellular prion protein on fyn kinase and ERK1/2 kinase
por: Tomasi, Vittorio
Publicado: (2010)

UbiSite: incorporating two-layered machine learning method with substrate motifs to predict ubiquitin-conjugation site on lysines
por: Huang, Chien-Hsun, et al.
Publicado: (2016)

Prediction of protein-protein interactions between viruses and human by an SVM model
por: Cui, Guangyu, et al.
Publicado: (2012)

Prion-like characteristics of the bacterial protein Microcin E492
por: Shahnawaz, Mohammad, et al.
Publicado: (2017)

Integrating protein-protein interactions and text mining for protein function prediction
por: Jaeger, Samira, et al.
Publicado: (2008)

Collective prediction of protein functions from protein-protein interaction networks
por: Wu, Qingyao, et al.
Publicado: (2014)

Choosing negative examples for the prediction of protein-protein interactions
por: Ben-Hur, Asa, et al.
Publicado: (2006)

Incorporating topological information for predicting robust cancer subnetwork markers in human protein-protein interaction network
por: Khunlertgit, Navadon, et al.
Publicado: (2016)

Identifying stage-specific protein subnetworks for colorectal cancer
por: Erten, Sinan, et al.
Publicado: (2012)

Inferring homologous protein-protein interactions through pair position specific scoring matrix
por: Lin, Chun-Yu, et al.
Publicado: (2013)

Integrating experimental and literature protein-protein interaction data for protein complex prediction
por: Zhang, Yijia, et al.
Publicado: (2015)

Scoring relevancy of features based on combinatorial analysis of Lasso with application to lymphoma diagnosis
por: Zare, Habil, et al.
Publicado: (2013)

The parasite specific substitution matrices improve the annotation of apicomplexan proteins
por: Ali, Jamshaid, et al.
Publicado: (2012)

A synopsis of eukaryotic N(α)-terminal acetyltransferases: nomenclature, subunits and substrates
por: Polevoda, Bogdan, et al.
Publicado: (2009)

A mixture of feature experts approach for protein-protein interaction prediction
por: Qi, Yanjun, et al.
Publicado: (2007)

Predicting cancer-associated germline variations in proteins
por: Martelli, Pier Luigi, et al.
Publicado: (2012)

Protein function prediction using domain families
por: Rentzsch, Robert, et al.
Publicado: (2013)

Integrating multiple networks for protein function prediction
por: Yu, Guoxian, et al.
Publicado: (2015)

PCDq: human protein complex database with quality index which summarizes different levels of evidences of protein complexes predicted from H-Invitational protein-protein interactions integrative dataset
por: Kikugawa, Shingo, et al.
Publicado: (2012)

Predicting multiplex subcellular localization of proteins using protein-protein interaction network: a comparative study
por: Jiang, Jonathan Q, et al.
Publicado: (2012)

Sequence-only evolutionary and predicted structural features for the prediction of stability changes in protein mutants
por: Folkman, Lukas, et al.
Publicado: (2013)

Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
por: Chen, Xiaoyu, et al.
Publicado: (2007)

A semi-supervised boosting SVM for predicting hot spots at protein-protein Interfaces
por: Xu, Bin, et al.
Publicado: (2012)

Applying internal coordinate mechanics to model the interactions between 8R-lipoxygenase and its substrate
por: Bai, Shuju, et al.
Publicado: (2010)

Functional site prediction selects correct protein models
por: Chelliah, Vijayalakshmi, et al.
Publicado: (2008)

Structure and function predictions of the Msa protein in Staphylococcus aureus
por: Nagarajan, Vijayaraj, et al.
Publicado: (2007)

Disease-related mutations predicted to impact protein function
por: Schaefer, Christian, et al.
Publicado: (2012)

Protein localization prediction using random walks on graphs
por: Xu, Xiaohua, et al.
Publicado: (2013)

Using Bacteria to Determine Protein Kinase Specificity and Predict Target Substrates
por: Chou, Michael F., et al.
Publicado: (2012)

Blocking Protein kinase C signaling pathway: mechanistic insights into the anti-leishmanial activity of prospective herbal drugs from Withania somnifera
por: Grover, Abhinav, et al.
Publicado: (2012)

Accuracy improvement in protein complex prediction from protein interaction networks by refining cluster overlaps
por: Chiam, Tak Chien, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_9hhs1car07p1bhgi2jolvpeucc