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12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone

There are two independent mol­ecules in the asymmetric unit of the title compound, C(30)H(44)O(5). They comprise a triterpenoid skeleton of five six-membered rings and a five-membered lactone ring. The five six-membered rings are all trans-fused. In both independent mol­ecules the D rings adopt a sl...

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Autores principales: Hu, Jun-yi, Wu, Gang-gang, Xu, Ying-qian, Xiao, Guo-yong, Lei, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379199/
https://www.ncbi.nlm.nih.gov/pubmed/22719397
http://dx.doi.org/10.1107/S1600536812017783
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author Hu, Jun-yi
Wu, Gang-gang
Xu, Ying-qian
Xiao, Guo-yong
Lei, Peng
author_facet Hu, Jun-yi
Wu, Gang-gang
Xu, Ying-qian
Xiao, Guo-yong
Lei, Peng
author_sort Hu, Jun-yi
collection PubMed
description There are two independent mol­ecules in the asymmetric unit of the title compound, C(30)H(44)O(5). They comprise a triterpenoid skeleton of five six-membered rings and a five-membered lactone ring. The five six-membered rings are all trans-fused. In both independent mol­ecules the D rings adopt a slightly distorted half-chair conformation due the presence of the lactone ring while the other four six-membered rings all adopt chair conformations. The characteristic carbon–carbon double bond of the oleanoic skeleton is absent. Inter­molecular O—H⋯O hydrogen bonds between the hy­droxy and carbonyl groups occur in the crystal structure.
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spelling pubmed-33791992012-06-20 12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone Hu, Jun-yi Wu, Gang-gang Xu, Ying-qian Xiao, Guo-yong Lei, Peng Acta Crystallogr Sect E Struct Rep Online Organic Papers There are two independent mol­ecules in the asymmetric unit of the title compound, C(30)H(44)O(5). They comprise a triterpenoid skeleton of five six-membered rings and a five-membered lactone ring. The five six-membered rings are all trans-fused. In both independent mol­ecules the D rings adopt a slightly distorted half-chair conformation due the presence of the lactone ring while the other four six-membered rings all adopt chair conformations. The characteristic carbon–carbon double bond of the oleanoic skeleton is absent. Inter­molecular O—H⋯O hydrogen bonds between the hy­droxy and carbonyl groups occur in the crystal structure. International Union of Crystallography 2012-05-02 /pmc/articles/PMC3379199/ /pubmed/22719397 http://dx.doi.org/10.1107/S1600536812017783 Text en © Hu et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Hu, Jun-yi
Wu, Gang-gang
Xu, Ying-qian
Xiao, Guo-yong
Lei, Peng
12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone
title 12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone
title_full 12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone
title_fullStr 12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone
title_full_unstemmed 12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone
title_short 12α-Hy­droxy-3,27-dioxooleanano-28,13-lactone
title_sort 12α-hy­droxy-3,27-dioxooleanano-28,13-lactone
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379199/
https://www.ncbi.nlm.nih.gov/pubmed/22719397
http://dx.doi.org/10.1107/S1600536812017783
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