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1-(Adamantan-1-ylcarbon­yl)-3-(2,6-difluoro-4-hy­droxy­phen­yl)thio­urea

In the title mol­ecule, C(18)H(20)F(2)N(2)O(2)S, the 2,6-difluoro-4-hy­droxy­phenyl ring and the carbonyl­thio­urea group are each essentially planar, with maximum deviations of atoms from their mean planes of 0.0113 (14) and 0.1017 (15) Å, respectively; the dihedral angle between these two planes i...

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Detalles Bibliográficos
Autores principales: Mohamed, Shaaban K., Jaber, Abdel-Aal M., Saeed, Sohail, Ahmad, Khuram Shahzad, Wong, Wing-Tak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379207/
https://www.ncbi.nlm.nih.gov/pubmed/22719405
http://dx.doi.org/10.1107/S1600536812018806
Descripción
Sumario:In the title mol­ecule, C(18)H(20)F(2)N(2)O(2)S, the 2,6-difluoro-4-hy­droxy­phenyl ring and the carbonyl­thio­urea group are each essentially planar, with maximum deviations of atoms from their mean planes of 0.0113 (14) and 0.1017 (15) Å, respectively; the dihedral angle between these two planes is 71.03 (6)°. An intra­molecular N—H⋯O hydrogen bond occurs. In the crystal, N—H⋯O and O—H⋯S hydrogen bonds connect the mol­ecules into chains running diagonally across the bc plane. C—H⋯S and C—H⋯F contacts are also observed.