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1-(Adamantan-1-ylcarbonyl)-3-(2,6-difluoro-4-hydroxyphenyl)thiourea
In the title molecule, C(18)H(20)F(2)N(2)O(2)S, the 2,6-difluoro-4-hydroxyphenyl ring and the carbonylthiourea group are each essentially planar, with maximum deviations of atoms from their mean planes of 0.0113 (14) and 0.1017 (15) Å, respectively; the dihedral angle between these two planes i...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379207/ https://www.ncbi.nlm.nih.gov/pubmed/22719405 http://dx.doi.org/10.1107/S1600536812018806 |
Sumario: | In the title molecule, C(18)H(20)F(2)N(2)O(2)S, the 2,6-difluoro-4-hydroxyphenyl ring and the carbonylthiourea group are each essentially planar, with maximum deviations of atoms from their mean planes of 0.0113 (14) and 0.1017 (15) Å, respectively; the dihedral angle between these two planes is 71.03 (6)°. An intramolecular N—H⋯O hydrogen bond occurs. In the crystal, N—H⋯O and O—H⋯S hydrogen bonds connect the molecules into chains running diagonally across the bc plane. C—H⋯S and C—H⋯F contacts are also observed. |
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