N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide

In the title compound, C(18)H(22)BrN(3)OS, the piperidine ring adopts a chair conformation. The mean plane of the thia­zole ring forms dihedral angles of 23.97 (10) and 75.82 (10)° with the mean planes of its adjacent benzene and piperidine rings, respectively. An intra­molecular N—H⋯N hydrogen bond...

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Detalles Bibliográficos
Autores principales: Ghabbour, Hazem A., Kadi, Adnan A., El-Subbagh, Hussein I., Chia, Tze Shyang, Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379262/
https://www.ncbi.nlm.nih.gov/pubmed/22719460
http://dx.doi.org/10.1107/S1600536812019204
Descripción
Sumario:In the title compound, C(18)H(22)BrN(3)OS, the piperidine ring adopts a chair conformation. The mean plane of the thia­zole ring forms dihedral angles of 23.97 (10) and 75.82 (10)° with the mean planes of its adjacent benzene and piperidine rings, respectively. An intra­molecular N—H⋯N hydrogen bond generates an S(7) ring motif in the mol­ecule. In the crystal, no significant inter­moelcular hydrogen bonds are observed, but a weak π–π inter­action with a centroid–centroid distance of 3.8855 (13) Å occurs.

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