N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide

In the title compound, C(18)H(22)BrN(3)OS, the piperidine ring adopts a chair conformation. The mean plane of the thia­zole ring forms dihedral angles of 23.97 (10) and 75.82 (10)° with the mean planes of its adjacent benzene and piperidine rings, respectively. An intra­molecular N—H⋯N hydrogen bond...

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Detalles Bibliográficos
Autores principales: Ghabbour, Hazem A., Kadi, Adnan A., El-Subbagh, Hussein I., Chia, Tze Shyang, Fun, Hoong-Kun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2012
Materias:
Organic Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379262/
https://www.ncbi.nlm.nih.gov/pubmed/22719460
http://dx.doi.org/10.1107/S1600536812019204
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author Ghabbour, Hazem A.
Kadi, Adnan A.
El-Subbagh, Hussein I.
Chia, Tze Shyang
Fun, Hoong-Kun
author_facet Ghabbour, Hazem A.
Kadi, Adnan A.
El-Subbagh, Hussein I.
Chia, Tze Shyang
Fun, Hoong-Kun
author_sort Ghabbour, Hazem A.
collection PubMed
description In the title compound, C(18)H(22)BrN(3)OS, the piperidine ring adopts a chair conformation. The mean plane of the thia­zole ring forms dihedral angles of 23.97 (10) and 75.82 (10)° with the mean planes of its adjacent benzene and piperidine rings, respectively. An intra­molecular N—H⋯N hydrogen bond generates an S(7) ring motif in the mol­ecule. In the crystal, no significant inter­moelcular hydrogen bonds are observed, but a weak π–π inter­action with a centroid–centroid distance of 3.8855 (13) Å occurs.
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spelling pubmed-33792622012-06-20 N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide Ghabbour, Hazem A. Kadi, Adnan A. El-Subbagh, Hussein I. Chia, Tze Shyang Fun, Hoong-Kun Acta Crystallogr Sect E Struct Rep Online Organic Papers In the title compound, C(18)H(22)BrN(3)OS, the piperidine ring adopts a chair conformation. The mean plane of the thia­zole ring forms dihedral angles of 23.97 (10) and 75.82 (10)° with the mean planes of its adjacent benzene and piperidine rings, respectively. An intra­molecular N—H⋯N hydrogen bond generates an S(7) ring motif in the mol­ecule. In the crystal, no significant inter­moelcular hydrogen bonds are observed, but a weak π–π inter­action with a centroid–centroid distance of 3.8855 (13) Å occurs. International Union of Crystallography 2012-05-12 /pmc/articles/PMC3379262/ /pubmed/22719460 http://dx.doi.org/10.1107/S1600536812019204 Text en © Ghabbour et al. 2012 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited.
spellingShingle Organic Papers
Ghabbour, Hazem A.
Kadi, Adnan A.
El-Subbagh, Hussein I.
Chia, Tze Shyang
Fun, Hoong-Kun
N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide
title N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide
title_full N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide
title_fullStr N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide
title_full_unstemmed N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide
title_short N-[4-(4-Bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide
title_sort n-[4-(4-bromo­phen­yl)thia­zol-2-yl]-4-(piperidin-1-yl)butanamide
topic Organic Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3379262/
https://www.ncbi.nlm.nih.gov/pubmed/22719460
http://dx.doi.org/10.1107/S1600536812019204
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